Clinical Trial: Topical Antiperspirant for Hand-Foot Syndrome
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Topical Antiperspirant for Prevention of Palmar-Plantar Erythrodysesthesia (Hand-Foot Syndrome) Associated With Capecitabine
Brief Summary: The objectives of this study are to evaluate the effectiveness of an antiperspirant in preventing or attenuating the severity of palmer-plantar erythrodysesthesia associated with the Food and Drug Administration (FDA)-approved doses of capecitabine. The hypothesis is that cytotoxic compounds in sweat will be prevented from being deposited in the skin and causing chronic toxicity.
Detailed Summary:
Sponsor: University of Wisconsin, Madison
Current Primary Outcome: reduction in palm and/or sole pain [ Time Frame: after each of first four cycles of chemotherapy ]
Original Primary Outcome: reduction in palm and/or sole pain
Current Secondary Outcome: evaluation of utility of digital photography in the following palmar-plantar erythrodysesthesia (PPES) [ Time Frame: after each of first four cycles of chemotherapy ]
Original Secondary Outcome: evaluation of utility of digital photography in the following PPES
Information By: University of Wisconsin, Madison
Dates:
Date Received: September 13, 2005
Date Started: May 2005
Date Completion:
Last Updated: October 1, 2015
Last Verified: December 2007