Clinical Trial: The Physalis Child : Identification of Cognitive and Emotional Factors

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: Identification of Cognitive and Emotional Factors in Relation to Auditory Hallucinations in Non-psychotic Children

Brief Summary: The aim of this study is to show presence of cognitive and emotional factors on the beginning and persistence of auditory hallucinations in non-psychotic children. Investigators will describe a significant link between this factors and hallucinations in a sample of non-psychotic children. The results of this sample will be comparing to another group of children of the same age, sex and diagnosis, but without hallucination. Finally, investigators will control the persistence of hallucination on the first group after a six month period.

Detailed Summary: Background: Hallucinations are a common symptom in pediatric population without psychotic syndrome. Vulnerability, co morbidity and risk factor are already been described. Investigators will study the cognitive and emotional factors on the beginning and persistence of auditory hallucinations in non-psychotic children. The goal of the study is to find a social cognition our emotional impairment to explain auditory hallucinations without psychotic symptoms. Methods: Sample of out non-psychotic patients aged six to eighteen years old with auditory hallucinations were recruited with a self report scale created for this study. Mini International Neuropsychiatric Interview (MINI)-kids interview and "psychosis" section od Kiddie-SADS (Schedule for Affective Disorders and Schizophrenia for school age chidlren) were conducted to determine Diagnostic and Statistical Manual of Mental Disorders (DSM) IV diagnoses. All children patient were spend specifics social cognition (NeuroPsychologic assessment NEPSY II) and emotional (ifferential Emotions Scale (DES) IV, Beliefs About Voices Questionnaire Revised (BAVQ-R)) scales. Each child results will be compared to child result of the same age, sex and diagnosis but without hallucination that passed the same specifics scales. All of child will be control after a six month period to evaluate auditory hallucination persistence and diagnosis evolution. The total period of the study will be twelve month.
Sponsor: Fondation Lenval

Current Primary Outcome: Evolution of the score of theory of mind [ Time Frame: Change from baseline 6 month later ]

The social cognitive marker will be evaluate by NeuroPsychologic assessment NEPSY II for theory of mind


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Evolution of the score of auditory hallucinations persistence [ Time Frame: Change from baseline 6 month later ]
    Evaluation of auditory hallucinations persistence with a self report scale using in recruiting criteria.
  • Evolution of the score of Mental Disorder [ Time Frame: Change from baseline 6 month later ]
    Evaluation of diagnosis of Mental Disorder with Diagnostic and Statistical Manual of Mental Disorders (DSM)-IV criteria using MINI-Kids (Mini International Neuropsychiatric Interview )
  • Evaluation of the score of Psychosis [ Time Frame: Change from baseline 6 month later ]
    Evaluation of diagnosis of psychosis with DSM-IV (Diagnostic and Statistical Manual of Mental Disorders ) criteria using "Psychosis" section of Kiddie-SADS (Schedule for Affective Disorders and Schizophrenia for school age chidlren)
  • Evolution of the score of individual stability [ Time Frame: Change from baseline 6 month later ]
    The evaluation of the the emotional marker will be performed with the Differential emotion scale IV (DES IV): emotional individual stability
  • Evolution of measure of recognition of the feelings [ Time Frame: Change from baseline 6 month later ]

    The measure of recognition of the feelings will be performed by the score:

    The social cognitive marker (NEPSY II)

  • Evolution of auditory measure of patients' emotional [ Time Frame: Change from baseline 6 month later ]

    The auditory measure will be performed by the score:

    The social cognitive marker (NEPSY II)

  • Evolution of Emotional real-life experience of the hallucination [ Time Frame: Change from baseline 6 month later ]

    The Emotional real-life experience of the hallucination will be performed by the score:

    The Revised Beliefs About Voices Questionnaire (BAVQ-R)

  • Evolution of the score of affect recognition [ Time Frame: Change from baseline 6 month later ]
    The social cognitive marker will be evaluate by NeuroPsychologic assessment NEPSY II for theory of affect recognition


Original Secondary Outcome: Same as current

Information By: Fondation Lenval

Dates:
Date Received: July 24, 2015
Date Started: July 2015
Date Completion: July 2016
Last Updated: October 2, 2015
Last Verified: October 2015