Clinical Trial: Understanding Hallucinations (Part I)
Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational
Official Title: Understanding Hallucinations (Part I) - Phenomenology and Cognition
Brief Summary: Psychotic symptoms (hallucinations and delusions) are present in several psychiatric and neurological disorders as well as in the general population. Effective treatment strategies for these symptoms in all patients are lacking and treatment-response can presently not be predicted. To date, the exact pathophysiological mechanism of these symptoms remains unknown. By investigating (subtypes) of hallucinations and delusions in all populations, a common pathway may be found, leading to more effective treatment options. Alternatively, different subtypes may be associated with different pathophysiological mechanisms.
Detailed Summary:
Sponsor: UMC Utrecht
Current Primary Outcome: The number of clusters of patients with shared symptom profiles as determined by latent class analysis, and the difference in scores on cognitive assessment between these identified clusters. [ Time Frame: Three years ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- The internal consistency, test-retest reliability, inter-rater reliability, criterion validity and construct validity of a newly developed questionnaire. [ Time Frame: Two years ]
- The difference in scores on cognitive assessment between participant groups with and without psychotic symptoms. [ Time Frame: Three years ]
Original Secondary Outcome: Same as current
Information By: UMC Utrecht
Dates:
Date Received: July 8, 2013
Date Started: June 2013
Date Completion: January 2018
Last Updated: October 25, 2016
Last Verified: October 2016
