Clinical Trial: Effectivity of Postpartum Dexamethasone for Women With Class I HELLP Syndrome

Study Status: Active, not recruiting
Recruit Status: Active, not recruiting
Study Type: Interventional

Official Title: Postpartum Dexamethasone for Women With Class I HELLP Syndrome: a Double-blind, Placebo-controled, Randomized Clinical Trial

Brief Summary: Corticotherapy accelerates maternal postpartum recovery in women with class I HELLP syndrome. The benefit of faster and better recovery would be observed in fewer complications, less utilization of blood products and shorter hospital stay.

Detailed Summary: Patients with Class I HELLP Syndrome will be recruited for use os dexamethasone or placebo in the puerperium. Effects such as clinical course (blood pressure and diureses), laboratorial behaviour and complications will be compared. Duration of hospitalization will also be accessed.
Sponsor: Instituto Materno Infantil Prof. Fernando Figueira

Current Primary Outcome: severe maternal morbidity [ Time Frame: postpartum ]

42 days after delivery


Original Primary Outcome:

  • platelet count [ Time Frame: postpartum behaviour ]
  • hospital stay [ Time Frame: postpartum behaviour ]


Current Secondary Outcome: hospital stay duration [ Time Frame: postpartum ]

Original Secondary Outcome: complications [ Time Frame: postpartum ]

Information By: Instituto Materno Infantil Prof. Fernando Figueira

Dates:
Date Received: July 7, 2008
Date Started: July 2011
Date Completion: March 2018
Last Updated: March 1, 2017
Last Verified: March 2017