Clinical Trial: Gastrointestinal Transit Time in Patients With Guillain-Barré Syndrome

Study Status: Suspended
Recruit Status: Suspended
Study Type: Observational

Official Title: Gastrointestinal Transit Time in Patients With Guillain-Barré Syndrome

Brief Summary: Constipation is a common condition among patients with Guillain-Barré Syndrome. It is believed, that the constipation is caused by autonomic neuropathy. However, the severity of the constipation, and its relation to autonomic function have not previously been studied.

Detailed Summary:
Sponsor: University of Aarhus

Current Primary Outcome: Gastrointestinal transit time (GITT) [in days] [ Time Frame: The measurement takes one week to perform. The investigators aim to start the measurement within one week after diagnosis. ]

Original Primary Outcome: Gastrointestinal transit time (GITT) [in days] [ Time Frame: The measurement takes one week to perform. The investigators aim to start the meaurement within one week after diagnosis. ]

Current Secondary Outcome: Association between heart rate variability (HRV) and GITT [ Time Frame: The first HRV measurement is performed within one week after diagnosis. The second is performed 7 days after the first. ]

Linear regression with GITT as dependent variable, and high frequency power spectral density analysis of the heart rate (HF) as the independent variable. The mean HF of the first and second HRV measurement is used for this regression.


Original Secondary Outcome: Same as current

Information By: University of Aarhus

Dates:
Date Received: May 18, 2015
Date Started: May 2015
Date Completion:
Last Updated: May 11, 2016
Last Verified: April 2015