Clinical Trial: Insulin Sensitivity and Substrate Metabolism Before and After Treatment in Patients With Growth Hormone Deficiency

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Insulin Sensitivity and Substrate Metabolism Before and After Treatment in Patients With Growth Hormone Deficiency

Brief Summary: The purpose of this study is to further characterize the treatment related changes in insulin sensitivity, substrate metabolism and intrahepatic-intramyocellular lipids in patients with growth hormone deficiency (GHD).

Detailed Summary:
Sponsor: University of Aarhus

Current Primary Outcome: insulin sensitivity [ Time Frame: before and after 3 months treatment with growth hormone ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

  • substrate metabolism [ Time Frame: before and after 3 months of growth hormone treatment ]
  • intrahepatic lipid content [ Time Frame: before and after 3 months of growth hormone treatment ]
  • intramyocellular lipid content [ Time Frame: before and after 3 months of growth hormone treatment ]


Original Secondary Outcome: Same as current

Information By: University of Aarhus

Dates:
Date Received: February 19, 2008
Date Started: March 2008
Date Completion:
Last Updated: October 21, 2009
Last Verified: October 2009