Clinical Trial: Garlic in Patients With Febrile Neutropenia
Study Status: Recruiting
Recruit Status: Unknown status
Study Type: Interventional
Official Title: A Controlled Study to Determine The Clinical Efficacy Of Garlic Compounds In Patients With Chemotherapy Related Febrile Neutropenia
Brief Summary: To determine the clinical effects of garlic in preventing and treatment of patients with chemotherapy related febrile neutropenia.These patients have a very high incidence of infections which are not routinely covered by the standard empiric therapy. Adding a non- toxic and possibly effective therapy may reduce the risk for infections, synergize the empiric antibiotic treatment and may lessen the need for broader spectrum and more severe side effects.
Detailed Summary: Patients eligible are randomized to receive placebo or garlic capsules after chemotherapy course and until leukocyte recovery.
Sponsor: Hadassah Medical Organization
Current Primary Outcome: Time to fever and beginning of empiric antibiotic treatment. [ Time Frame: 0-45 days post chemotherapy ]
Original Primary Outcome: •Time to fever and beginning of empiric antibiotic treatment.
Current Secondary Outcome:
- Documented and culture positive infections. [ Time Frame: as above ]
- Kind of infectious organisms and sensitivity to medicines. [ Time Frame: as above ]
- Length of infection [ Time Frame: as above ]
- Use of growth factors. [ Time Frame: as above ]
Original Secondary Outcome:
- • Documented and culture positive infections.
- • Kind of infectious organisms and sensitivity to medicines.
- • Length of infection
- • Use of growth factors.
Information By: Hadassah Medical Organization
Dates:
Date Received: October 31, 2005
Date Started: June 2006
Date Completion: August 2013
Last Updated: July 4, 2013
Last Verified: July 2013
