Clinical Trial: Pompe Disease QMUS and EIM

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: Electrical Impedance Myography and Muscle Ultrasound: Longitudinal Measures in Pompe Disease

Brief Summary:

Study Objectives:

  1. Determine the correlation between quantitative muscle ultrasound (QMUS), electrical impedance myography (EIM) and currently accepted measures of physical function.
  2. Determine the reliability of EIM measures performed in the home through use of a hand held device.
  3. Determine if QMUS and EIM can detect pre-clinical changes in Pompe disease.

Detailed Summary:
Sponsor: Duke University

Current Primary Outcome:

  • Percent change in muscle ultrasound echointensity as compared to baseline [ Time Frame: Baseline, 1-2 years ]
  • Percent change in muscle electrical impedance myography as compared to baseline [ Time Frame: Baseline, 1-2 years ]


Original Primary Outcome: Same as current

Current Secondary Outcome: Inter-rater reliability of muscle ultrasound and electrical impedance myography measures [ Time Frame: 1-2 years ]

Original Secondary Outcome: Same as current

Information By: Duke University

Dates:
Date Received: April 11, 2016
Date Started: October 2016
Date Completion:
Last Updated: March 24, 2017
Last Verified: October 2016