Clinical Trial: Pompe Disease QMUS and EIM
Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional
Official Title: Electrical Impedance Myography and Muscle Ultrasound: Longitudinal Measures in Pompe Disease
Brief Summary:
Study Objectives:
- Determine the correlation between quantitative muscle ultrasound (QMUS), electrical impedance myography (EIM) and currently accepted measures of physical function.
- Determine the reliability of EIM measures performed in the home through use of a hand held device.
- Determine if QMUS and EIM can detect pre-clinical changes in Pompe disease.
Detailed Summary:
Sponsor: Duke University
Current Primary Outcome:
- Percent change in muscle ultrasound echointensity as compared to baseline [ Time Frame: Baseline, 1-2 years ]
- Percent change in muscle electrical impedance myography as compared to baseline [ Time Frame: Baseline, 1-2 years ]
Original Primary Outcome: Same as current
Current Secondary Outcome: Inter-rater reliability of muscle ultrasound and electrical impedance myography measures [ Time Frame: 1-2 years ]
Original Secondary Outcome: Same as current
Information By: Duke University
Dates:
Date Received: April 11, 2016
Date Started: October 2016
Date Completion:
Last Updated: March 24, 2017
Last Verified: October 2016