Clinical Trial: Efficacy and Safety of Losartan in Children With Ig A Nephropathy
Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional
Official Title: A Prospective Study Evaluating the Efficacy and Safety of Losartan in Children With Immunoglobulin A Nephropathy
Brief Summary: The investigators hypothesize that using Losartan would help decrease proteinuria in controlling proteinuria in children with immunoglobulin A nephropathy.
Detailed Summary:
Sponsor: Seoul National University Hospital
Current Primary Outcome: the change in urinary protein-creatinine ratio from baseline to the end of study [ Time Frame: 24weeks ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- the change in urinary albumin-creatinine ratio from baseline to the end of study [ Time Frame: 24 weeks ]
- the proportion of patients wifh more than 50% decrease of urinary protein-creatinine ratio [ Time Frame: 24 weeks ]
- the proportion of patients wifh urinary protein-creatinine ratio < 0.2 at the end of study [ Time Frame: 24 weeks ]
Original Secondary Outcome: Same as current
Information By: Seoul National University Hospital
Dates:
Date Received: September 3, 2014
Date Started: October 2014
Date Completion: November 2016
Last Updated: November 16, 2015
Last Verified: November 2015
