Clinical Trial: Autonomic Nervous System (ANS) and Renal Function in Immunoglobin A (IgA) Nephropathy

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Autonomic Nervous System (ANS) Analysis According to Different Renal Function Stage in Immunoglobin A (IgA) Nephropathy

Brief Summary:

The estimation of the cardiovascular risk in the general population must take into account small renal disturbances, as the microalbuminuria. Conversely certain parameters of the cardiovascular risk influence the evolution of renal diseases, for example the arterial high blood pressure.

The measure of the activity of the autonomous nervous system, and especially the quantification of its variability, is a means to estimate the cardiovascular risk. The investigators formulate the hypothesis that the variability of the autonomous nervous system is an additional clinical element for the evaluation of the evolutionary risk of renal diseases.

The aim of this study is to compare the variability of the autonomous nervous system during the various evolutionary stages of the renal disease.

The renal disease studied will be IgA nephropathy (IgNA). IgNA is a histologically defined glomerulonephritis (rela biopsy) by the presence of deposits immunoglobulin A (IgA) in the renal mesangium (at list 1+) by immunofluorescence.


Detailed Summary:
Sponsor: Centre Hospitalier Universitaire de Saint Etienne

Current Primary Outcome: Standard deviation of all R-R intervals (SDNN) [ Time Frame: day 1 ]

Comparison of Standard deviation of all R-R intervals (SDNN) between GFR category of IgNA


Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Centre Hospitalier Universitaire de Saint Etienne

Dates:
Date Received: August 18, 2015
Date Started: January 2011
Date Completion:
Last Updated: August 18, 2015
Last Verified: August 2015