Clinical Trial: Antimicrobial Photodynamic Therapy as an Adjunct Treatment for Periodontal Disease in Down's Syndrome Patients
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Full-mouth Antimicrobial Photodynamic Therapy as an Adjunct to Non-surgical Periodontal Disease Treatment in Down's Syndrome Patients
Brief Summary:
The aim of this study was to evaluate the effectiveness of antimicrobial photodynamic therapy as an adjuvant of scaling and root planning for treatment of periodontal disease in patients with Down's Syndrome. After scaling and root planning, half of patients received antimicrobial photodynamic therapy with methylene blue dye and laser and the sessions were repeated after 3, 7 and 14 days. The other half received only scaling and root planning.
Detailed Summary: Antimicrobial photodynamic therapy (aPDT) has been widely used in Periodontics to obtain reduction of periodontopathogenic bacteria with absence of systemic side effects and minimal bacterial resistance. Therefore, a good adjuvant alternative for periodontal disease treatment arises, especially for patients with Down syndrome (DS) who present greater severity and high prevalence of periodontal disease. Usually aPDT is used as an adjunct therapy to scaling and root planning.
Sponsor: University of Sao Paulo
Current Primary Outcome: Periodontal disease (gingivitis and periodontitis) measured by a periodontal probe and classified according to severity [ Time Frame: one year ]
Original Primary Outcome: Same as current
Current Secondary Outcome: Obesity measured by a tape and a scale [ Time Frame: one day ]
Original Secondary Outcome: Same as current
Information By: University of Sao Paulo
Dates:
Date Received: October 18, 2016
Date Started: October 2013
Date Completion:
Last Updated: October 18, 2016
Last Verified: October 2016