Clinical Trial: Pulmonary Mechanics During Minimally Invasive Repair of Pectus Excavatum

Study Status: Recruiting
Recruit Status: Unknown status
Study Type: Interventional

Official Title: Phase 4 Study of Desflurane and Sevoflurane That Affect Pulmonary Mechanics During Minimally Invasive Repair of Pectus Excavatum

Brief Summary: The aim of the current study was to compare the effects of sevoflurane and desflurane on respiratory mechanics in patients undergoing repair of pectus excavatum.

Detailed Summary: The minimally invasive technique for pectus excavatum repair was introduced by Nuss and colleagues using a metal bar to lift the depressed chest wall. This surgical procedure is usually done under general anesthesia with tracheal intubation. After inserting metal bar into the chest wall, decreased lung compliance was shown. Previous studies demonstrated that administering desflurane during anesthesia resulted in marked increases in respiratory mechanical parameters, especially in the children with airway susceptibility. Our primary hypothesis was that desflurane would cause an increase in respiratory resistance and a decrease in lung compliance compared to sevoflurane during repair of pectus excavatum.
Sponsor: The Catholic University of Korea

Current Primary Outcome: pulmonary mechanics [ Time Frame: within the 2 hours during the surgery ]

Original Primary Outcome: Same as current

Current Secondary Outcome: complication [ Time Frame: within 72 hours after sugery ]

Original Secondary Outcome: complication [ Time Frame: within 72 hours after sugery ]

Information By: The Catholic University of Korea

Dates:
Date Received: November 26, 2011
Date Started: November 2011
Date Completion: April 2014
Last Updated: July 22, 2013
Last Verified: July 2013