Clinical Trial: Preventing Infections in Orthopaedic Patients
Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Observational
Official Title: Antibiotic Prophylaxis for Type II and III Open Fractures: a Retrospective Chart Review
Brief Summary: Determine if antibiotic prophylaxis with intravenous cephalosporin and aminoglycoside in patients with Type II and II open fractures is safe and effective.
Detailed Summary:
- Determine the safety and efficacy of antibiotic prophylaxis in type II and II open fractures when using IV Cephalosporin and aminoglycoside.
- Identify the incidence of acute kidney injury.
- Identify the type and number of associated infections
- Identify the antibiotic resistance profile noted
- Identify any secondary infections at sites other than the fracture site
Sponsor: Olayemi Osiyemi MD
Current Primary Outcome: Rate of fracture site infections [ Time Frame: 30 days ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Incidence of acute renal injury [ Time Frame: 30 days ]number of patients with worsening renal function from baseline
- type of bacteria infection [ Time Frame: 30 days ]name of bacteria infection
- resistance trend in patients with infections [ Time Frame: 30 days ]describe the number of MDRO infections
- number of secondary infections at site other than fracture sites [ Time Frame: 30 days ]describe the number infections at secondary sites
Original Secondary Outcome: Same as current
Information By: Triple O Research Institute PA
Dates:
Date Received: October 14, 2016
Date Started: November 2016
Date Completion: February 2018
Last Updated: October 26, 2016
Last Verified: October 2016