Clinical Trial: Antibiotic Prophylaxis in Open Fractures

Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Interventional

Official Title: Antibiotic Prophylaxis With Ceftaroline for Type II and II Open Fractures: a Phase 4, Open-label, Prospective Clinical Trial

Brief Summary: Prospective look at antibiotic prophylaxis with Ceftaroline in patients with type II and III open fractures

Detailed Summary: Determine if antibiotic prophylaxis with Ceftaroline in patients with type II and III open fractures is a safe and effective alternative to standard combination therapy
Sponsor: Olayemi Osiyemi MD

Current Primary Outcome: Rate of fracture site infection at 30 days between ceftaroline and historical hospital rate [ Time Frame: 30 days ]

Original Primary Outcome: Same as current

Current Secondary Outcome: Incidence of acute kidney injury [ Time Frame: 30 days ]

Original Secondary Outcome: Same as current

Information By: Triple O Research Institute PA

Dates:
Date Received: October 14, 2016
Date Started: December 2016
Date Completion: March 2019
Last Updated: October 26, 2016
Last Verified: October 2016