Clinical Trial: Early Bolus Surfactant Replacement Therapy Versus Standard Care in Term Neonates With Meconium Aspiration Syndrome

Study Status: RECRUITING
Recruit Status: RECRUITING
Study Type: INTERVENTIONAL

Official Title: Early Bolus Surfactant Replacement Therapy Versus Standard Care in Term (>=37 Weeks) Neonates With Actant Replacement Therapy Versus Standard Care in Term Neonates With Meconium Aspiration Syndrome

Brief Summary: The objective of the study is to compare the total duration of respiratory support in term neonates (?37weeks) with meconium aspiration syndrome, who are provided early(?2hr) bolus surfactant therapy versus standard care.

Detailed Summary:

Enrolled participants will be randomly assigned to one of two study groups: 1. early(?2hr) bolus surfactant replacement therapy or 2. standard care

Intervention group: The neonates enrolled in this group will receive early bolus surfactant replacement therapy within 2hr of life.

Control group: The neonates enrolled in this group will receive standard care according to standard unit protocol

Sponsor: Lady Hardinge Medical College

Current Primary Outcome: Combined duration of invasive + non invasive ventilation

Original Primary Outcome: Combined duration of invasive + non invasive ventilation

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Lady Hardinge Medical College

Dates:
Date Received: October 13, 2023
Date Started: March 12, 2022
Date Completion: March 12, 2024
Last Updated: October 13, 2023
Last Verified: October 01, 2023