Clinical Trial: Supernormal Goal for Proximal Femur Fracture

Study Status: Active, not recruiting
Recruit Status: Unknown status
Study Type: Observational

Official Title: Supernormal Oxygen Delivery May Not be a Valid Goal for Patients With Proximal Femur Fracture. An Observational Pilot Study

Brief Summary: This is an observational pilot study of supernormal oxygen delivery goal for patients with proximal femoral fracture.

Detailed Summary: Augmentation of oxygen delivery using fluids with or without inotropes has been shown to improve surgical outcome in high-risk patients. Patients with proximal femoral fracture are considered high risk. However, most of this cohort elderly patients have poor cardiovascular condition and may not achieve the oxygen delivery goal. We will perform an observational pilot study whether the supernormal oxygen delivery is a valid hemodynamic goal for patients with proximal femoral fracture.
Sponsor: Guangzhou First People's Hospital

Current Primary Outcome: Oxgen delivery index [ Time Frame: At the end of 4 hour goal-directed therapy ]

To attain a improved oxygen delivery index at the end of 4 hour goal-directed therapy


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Hear rate augmentation [ Time Frame: Day 1 ]
  • Hemodynamic response [ Time Frame: Day 1 ]
    Including stroke volume, cardiac index, base excess, lactate, hemoglobin, and urine output.
  • fluid volume administrated [ Time Frame: intraoperatively ]
  • Length of hospital stay [ Time Frame: Day 30 ]
  • Postoperative morbidity [ Time Frame: day 5 ]


Original Secondary Outcome: Same as current

Information By: Guangzhou First People's Hospital

Dates:
Date Received: July 14, 2014
Date Started: August 2014
Date Completion: June 2015
Last Updated: July 16, 2014
Last Verified: July 2014