Clinical Trial: Platelet-rich Plasma Versus Corticosteroid Injection for the Treatment of Femoroacetabular Impingement
Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional
Official Title: Platelet-rich Plasma Versus Corticosteroid Injection for the Treatment of Femoroacetabular Impingement
Brief Summary: The purpose of this study is to compare the clinical response of intra-articular platelet rich plasma (PRP) versus corticosteroid injection in patients affected by femoroacetabular impingement (FAI).
Detailed Summary: This study will determine if PRP treatment of FAI improves (i) patient reported outcome scores and (ii) hip functional stability compared to standard corticosteroid treatment and if PRP treatment of FAI reduces (i) radiographic and (ii) biochemical markers of joint inflammation and cartilage degradation.
Sponsor: University of Michigan
Current Primary Outcome: Change from baseline in pain score on the visual analog scale at 6 months [ Time Frame: 12 months ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Hip Disability and Osteoarthritis Outcome Score (HOOS), Western Ontario and McMaster Universities Arthritis Index (WOMAC), calculated as a sub-score of the HOOS [ Time Frame: 12 months ]
- Patient Reported Outcome Measurement Information System (PROMIS) Global Health Scale [ Time Frame: 12 months ]
- Serum Biomarker analysis: IFN-g, IL-6, MCP-1, MIP-1b, IL-1b, TNF-alpha, highly sensitive CRP, COMP. [ Time Frame: 12 months ]
Original Secondary Outcome: Same as current
Information By: University of Michigan
Dates:
Date Received: August 30, 2016
Date Started: August 2016
Date Completion: July 2018
Last Updated: September 28, 2016
Last Verified: September 2016
