Clinical Trial: Muscle Relaxation for Short Procedures
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Comparing Intubating Conditions and Patient Satisfaction Using Succinylcholine or Low-dose Rocuronium for Rigid Bronchoscopy: A Randomized Study
Brief Summary: Succinylcholine is commonly used for neuromuscular relaxation for short procedures such as rigid bronchoscopy. A more modern alternative is the application of low-dose rocuronium, reversed by low-dose sugammadex. The investigators compare the intubating conditions, incidence of postoperative myalgia (POM), as well as patient satisfaction for these two muscle relaxants.
Detailed Summary:
Sponsor: Dr. Horst Schmidt Klinik GmbH
Current Primary Outcome: Intubating condition [ Time Frame: After induction of general anaesthesia (after 3-5 minutes) ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Fasciculations [ Time Frame: After application of the neuromuscular blocking agent (after 3-5 min) ]
Fasciculations were graded by the investigator on the following four-point scale
0 = no fasciculations
- = mild, fine fasciculations of the eyes, neck, face or fingers, without limb movement
- = moderate fasciculations occurring at more than two sites, or obvious limb movement
- = vigorous or severe, sustained and widespread fasciculations in the trunk and limbs
- Postoperative Myalgia (POM) [ Time Frame: 72 Hours after Intervention ]
The severity of POM was measured using a four-point scale 0 = no myalgia
- = minor pain limited to one area of the body
- = muscle pain or stiffness noticed spontaneously by the patient, which may have required analgesic therapy
- = generalized, severe, or incapacitating discomfort
Original Secondary Outcome: Same as current
Information By: Dr. Horst Schmidt Klinik GmbH
Dates:
Date Received: July 9, 2013
Date Started: October 2011
Date Completion:
Last Updated: July 16, 2013
Last Verified: July 2013