Clinical Trial: Towards Individualized Surgery in Non-focal Congenital Hyperinsulinism
Study Status: Completed
Recruit Status: Completed
Study Type: Observational
Official Title: Towards Individualized Surgery in Non-focal Congenital Hyperinsulinism
Brief Summary: Observational study in patients with non-focal congenital hyperinsulinism showing that restrictive surgery may improve the metabolic situation
Detailed Summary: In non-focal congenital hyperinsulinism (CHI) the current doctrine warrants subtotal pancreatic resection in all children who do not respond to medication. However, the rate of diabetes after these extensive resections is very high. In this study investigators show that a less aggressive approach may suffice to wean many children from all medication or to get them manageable medically.
Sponsor: University Medicine Greifswald
Current Primary Outcome: necessity of medication after restrictive surgery in congenital hyperinsulinism [ Time Frame: up to 3 years ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
Original Secondary Outcome:
Information By: University Medicine Greifswald
Dates:
Date Received: March 28, 2014
Date Started: March 2011
Date Completion:
Last Updated: April 8, 2014
Last Verified: April 2014