Clinical Trial: Detection of Chlamydia DNA by Polymerase Chain Reaction in Primary Tubal and Ovarian Cancers Tissues : a Pilot Study

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational

Official Title: Detection of Chlamydia DNA by Polymerase Chain Reaction ( PCR ) in Tumours Tissue of Primary Tubal and Ovarian Cancers : a Pilot Study

Brief Summary: PCR for chlamydia DNA is done in paraffin blocks of cases of primary tubal cancer and is compared to cases of high grade serous ovarian cancer and normal tubes .

Detailed Summary: The investigators shall review the early cancer detection unite pathology records for the past 10 years , for cases diagnosed with primary Fallopian tube cancers , cases of high and low grade serous ovarian cancer and cases underwent hysterectomy and salpingectomy for non oncological reasons. Paraffin blocks for suitable selected patients will be examined histologically to confirm the primary diagnosis . Chlamydia DNA in these paraffin blocks of the Fallopian tubes and ovarian tissues will be examined using PCR techniques . The possible correlation between the presence of Chlamydia DNA and the ovarian serous tumours and primary tubal cancer will be analyzed statistically .
Sponsor: Ain Shams University

Current Primary Outcome: Presence of chlamydia DNA in tubal and ovarian tissues [ Time Frame: Up to 24 weeks ]

Original Primary Outcome: Same as current

Current Secondary Outcome: Presence of concomitant tubal cancer with high grade serous ovarian cancer [ Time Frame: Up to 8 weeks ]

Original Secondary Outcome: Same as current

Information By: Ain Shams University

Dates:
Date Received: January 10, 2015
Date Started: January 2015
Date Completion: March 2016
Last Updated: October 28, 2015
Last Verified: October 2015