Clinical Trial: Wound Healing Abnormalities in Major Abdominal Surgery

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: Incidence of Wound-healing-abnormalities in Major Abdominal Surgery - Association With Factors of Coagulation

Brief Summary: This clinical observational study investigates the incidence of wound healing abnormalities in patients undergoing major abdominal surgery. Second aim of the study is, if wound healing deficits may be accompanied by abnormalities in blood coagulation parameters.

Detailed Summary:
Sponsor: Klinikum St. Georg gGmbH

Current Primary Outcome: Incidence of wound healing abnormalities [ Time Frame: from baseline to postoperative day 28 ]

Occurence of wound healing abnormalities within the first 28 days after surgery


Original Primary Outcome: Incidence of wound healing abnormalities [ Time Frame: postoperative day 4, day 7, day 28 ]

Current Secondary Outcome: Abnormalities in coagulation parameters [ Time Frame: postoperative day 28 ]

occurence of low platelets (<60.000) or factor XIII < 50% between the first and seventh postoperative day


Original Secondary Outcome:

  • Abnormalities in coagulation parameters [ Time Frame: postoperative day 1-4, day 7 ]
  • Expression of extracellular matrix proteins [ Time Frame: postoperative day 1-4, day 7 ]


Information By: Klinikum St. Georg gGmbH

Dates:
Date Received: August 14, 2008
Date Started: July 2008
Date Completion:
Last Updated: April 21, 2017
Last Verified: April 2017