Clinical Trial: Postoperative Analgesia in Patients With Microvascular Decompression

Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Interventional

Official Title: Efficacy and Safety of Multimodal Analgesia Used in Patients With Microvascular Decompression

Brief Summary: Perioperative pain is caused by a variety of harmful factors through multiple mechanisms, therefore, reasonable postoperative analgesia should be combined with drugs or measures of different mechanism , which is called multimodal analgesia. Multimodal analgesia could minimize side effects and achieve a better analgesic effect. Commonly used strategies of multimodal analgesia are oral analgesic drug, nerve block, patient controlled analgesia and so on. This study will observe the effect of multimodal analgesia on postoperative pain in patients with microvascular decompression and record side effects. Finally, it will provide technical support for the guidance of postoperative analgesia in patients of trigeminal neuralgia.

Detailed Summary: The investigators will collect 90 cases which will be divided into 3 groups. Patients in Group A will receive scalp nerve block and patient-controlled analgesia which contains sufentanil and ondansetron. In Group B, patient-controlled analgesia which contains sufentanil, ondansetron and ketamine will be applied. In Group C, patient-controlled analgesia which contains sufentanil and ondansetron will be applied.
Sponsor: Xiangya Hospital of Central South University

Current Primary Outcome: visual analog scale score [ Time Frame: 6 hour after operation ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Xiangya Hospital of Central South University

Dates:
Date Received: May 4, 2017
Date Started: May 15, 2017
Date Completion: May 15, 2018
Last Updated: May 12, 2017
Last Verified: May 2017