Clinical Trial: Study of Ocular Penetration of Topically Administered Fluoroquinolones
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Parallel-group Study of Ocular Penetration of Peri-operative Topically Administered Fluoroquinolones With Cataract Surgery
Brief Summary: This study is being conducted to evaluate the intraocular penetration of Moxifloxacin 0.5% ophthalmic solution (Vigamox) and Besifloxacin 0.6% ophthalmic suspension (Besivance) after pre-operative topical administration in subjects undergoing cataract surgery.
Detailed Summary:
Sponsor: Johns Hopkins University
Current Primary Outcome: Aqueous Humor Concentration of Study Drug [ Time Frame: approximately 3 to 4 months ]
Original Primary Outcome: Aqueous Humor Concentration of Study Drug [ Time Frame: The aqueous humor sample will be obtained at the onset of cataract surgery ]
Current Secondary Outcome: Disk Diffusion Assay of Collected Aqueous Humor [ Time Frame: Approximately 3-4 months. ]
Original Secondary Outcome:
Information By: Johns Hopkins University
Dates:
Date Received: June 5, 2009
Date Started: September 2009
Date Completion:
Last Updated: May 25, 2010
Last Verified: November 2009