Clinical Trial: Pediatric Relapsing Polychondritis : Diagnosis and Management in a French Retrospective Study

Study Status: RECRUITING
Recruit Status: RECRUITING
Study Type: OBSERVATIONAL

Official Title: Pediatric Relapsing Polychondritis : Diagnosis and Management in a French Retrospective Study

Brief Summary:

The incidence in pediatrics is very low (about 3.5 per million per year according to a 2015 study) and therefore the data on the pathology very poor, especially on the therapeutic level.

Without appropriate treatment, the disabling sequelae, even involving the vital prognosis, are significant.
However, in paediatrics, therapeutic habits have been extrapolated from adult data and lack precision.

Existing treatments are almost composed of immunomodulatory and/or immunosuppressive treatments.
Different therapeutic lines have been introduced over the years and a better understanding of the pathology.
More recently, biotherapies have been introduced in this pathology, but data on their effectiveness remain limited.
Data on the evolution under therapy in children are thus still poor.

Complications related to the pathology that can jeopardize the vital prognosis and the response to treatment for this pathology deserve to be studied in order to be known and if possible avoided.

The aim of the study is to describe French practices and compare the lines of treatment proposed for juvenile atrophic polychondritis.

Detailed Summary:
Sponsor: University Hospital, Strasbourg, France

Current Primary Outcome: The aim of this study is to bring together the experiences of the various reference and competence centers in France concerning the clinical presentation, management and follow-up of children with relapsing polychondritis.

Original Primary Outcome: The aim of this study is to bring together the experiences of the various reference and competence centers in France concerning the clinical presentation, management and follow-up of children with relapsing polychondritis.

Current Secondary Outcome:

Original Secondary Outcome:

Information By: University Hospital, Strasbourg, France

Dates:
Date Received: August 24, 2023
Date Started: February 18, 2023
Date Completion: January 18, 2024
Last Updated: October 30, 2023
Last Verified: August 01, 2023