Clinical Trial: Early Diagnosis in Glaucoma With GDxVcc

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: Evaluation of Scanning Laser Polarimetry Findings in Individuals With Exfoliation Syndrome Compared With Normal Controls

Brief Summary: To compare the Retina Nerve Fiber Layer thickness, measured with Scanning Laser Polarimetry in subjects with exfoliation syndrome and normal controls and to evaluate the value of scanning laser polarimetry in the early diagnosis and management of exfoliative glaucoma

Detailed Summary: To compare the Scanning Laser Polarimetry findings in subjects with exfoliation syndrome and normal controls and to evaluate the value of scanning laser polarimetry in the early diagnosis and management of exfoliative glaucoma. Prospective study in progress. The investigators compare and analyze the scanning laser polarimetry parameters in consecutive subjects with exfoliation syndrome and normal intraocular pressure and compared them with consecutive normal controls. Randomly selected patients with exfoliation syndrome and normal controls undergo a comprehensive ophthalmic exam which includes 3 IOP measurements, corneal pachymetry, automated perimetry and assessment of the retina nerve fiber layer with scanning laser polarimetry. The investigators hypothesize that patients with exfoliation syndrome may show worse scanning laser polarimetry parameters than normal controls and this may prove to be an early sign of exfoliative glaucoma development. Evaluation of retina nerve fiber layer thickness may help us in identifying earlier those individuals with exfoliation syndrome that will develop exfoliative glaucoma.
Sponsor: Aristotle University Of Thessaloniki

Current Primary Outcome: Scanning laser polarimetry parameters, evaluation of retina nerve fiber layer thickness [ Time Frame: Morning measurement (10:00 - 13:00) ]

Original Primary Outcome: Same as current

Current Secondary Outcome: Corneal thickness, exfoliation syndrome subjects that will develop exfoliation glaucoma [ Time Frame: 10:00-13:00 ]

Original Secondary Outcome: Same as current

Information By: Aristotle University Of Thessaloniki

Dates:
Date Received: November 30, 2009
Date Started: September 2007
Date Completion:
Last Updated: May 9, 2014
Last Verified: May 2014