Clinical Trial: Peri-operative Oral Triiodothyronine Replacement Therapy to Decrease the Risk of Transient Atrial Fibrillation After Off-pump Coronary Artery Bypass Surgery
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Peri-operative Oral Triiodothyronine Replacement Therapy to Decrease the Risk of Transient Atrial Fibrillation After Off-pump Coronary Artery Bypass Surgery
Brief Summary: This study is planned to medicate oral T3(Liothyronine)to the patients who are planned to have OPCAB(off- pump coronary bypass graft surgery. The aim of this study was to assess the effects of oral triiodothyronine (T3) therapy on postoperative thyroid hormone concentrations, hemodynamic variables and outcomes in patients undergoing OPCAB in a randomized, controlled trial.
Detailed Summary:
Sponsor: Yonsei University
Current Primary Outcome: compare the serum T3 concentrations and the number of patients with serum T3 concentrations below the normal range between the groups [ Time Frame: until 36 hours after surgery ]
Original Primary Outcome:
Current Secondary Outcome: difference of hemodynamic performance and myocardial injury [ Time Frame: during surgery and 36 hr after surgery ]
Original Secondary Outcome:
Information By: Yonsei University
Dates:
Date Received: June 29, 2010
Date Started: June 2010
Date Completion:
Last Updated: July 23, 2012
Last Verified: July 2012