Clinical Trial: Levothyroxine for Children With Euthyroid Sick Syndrome
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Efficacy and Safety of Levothyroxine in Critical Children With Euthyroid Sick Syndrome in a Pediatric Intensive Care Unit.
Brief Summary: The purpose of this study is to determine whether levothyroxine is effective and safe in the treatment of children with euthyroid sick syndrome, hospitalized in a pediatric intensive care unit.
Detailed Summary: Children with euthyroid sick syndrome, hospitalized in a pediatric intensive care unit, will be randomised to receive either Levothyroxine or placebo, to determine if it diminishes mortality.
Sponsor: Sinaloa Pediatric Hospital
Current Primary Outcome: All cause mortality [ Time Frame: participants will be followed for the duration of hospital stay, an expected average of 3 weeks ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Length of time in intensive care [ Time Frame: participants will be followed for the duration of hospital stay, an expected average of 2 weeks ]
- Ventilation days [ Time Frame: participants will be followed for the duration of hospital stay, an expected average of 2 weeks ]
- Use of vasopressors [ Time Frame: participants will be followed for the duration of hospital stay, an expected average of 3 weeks ]
- Thyroid hormones levels [ Time Frame: participants will be followed for the duration of hospital stay, an expected average of 3 weeks ]
Original Secondary Outcome: Same as current
Information By: Sinaloa Pediatric Hospital
Dates:
Date Received: June 26, 2012
Date Started: January 2012
Date Completion:
Last Updated: March 4, 2014
Last Verified: March 2014
