Clinical Trial: Long-Term Outcomes in the Treatment of Infantile and Acquired Esotropia With Botulinum Toxin

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: Long-Term Outcomes in the Treatment of Infantile and Acquired Esotropia With Botulinum Toxin

Brief Summary: To investigate long-term treatment outcomes of patients receiving botulinum toxin A therapy for infantile and acquired esotropia.

Detailed Summary:

Participants: 164 patients with infantile esotropia and 89 patients with acquired esotropia.

Methods: Patients were injected with botulinum toxin into two medial rectus muscles and followed from 1992 to 2005. Patients were evaluated at 1 week, 2, 6 and 12 months, and then yearly post-injection.

Main Outcome Measures: Degree of motor alignment, recurrence rate, incidence of stereopsis, and dissociated vertical deviation along with complications.

Sponsor: National Taiwan University Hospital

Current Primary Outcome: Degree of motor alignment, recurrence rate, incidence of stereopsis, and dissociated vertical deviation along with complications. [ Time Frame: Before treatment, weekly after the treatment, and monthly after motor alignment ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: National Taiwan University Hospital

Dates:
Date Received: August 31, 2008
Date Started: September 2007
Date Completion:
Last Updated: August 31, 2008
Last Verified: September 2007