Clinical Trial: Vascular and Neurologic Exploration of Small Nervous Fiber by Sudoscanner and QST

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: Vascular and Neurologic Exploration of Small Nervous Fiber by Sudoscanner

Brief Summary:

Erythromelalgy (EM) is a vascular syndrome very rare affecting the feet. This disease evolve by crisis when the feet extremities become red hot and painful. There are several types of EM but this study concern the adult primitive form. For a long time, the physiopathology was not described but now we know that there is a vascular form, with microcirculatory dysfunction and a neurologic form with small fibers neuropathy. The diagnostic of neurologic form is based on clinical evaluation (DN4 questionnaire, UENS scale...) and an electromyography. Thermotest, a medical device which measure the thermic sensitivity is used to quantify neuropathy. More recently Sudoscan, a device measuring cutaneous impedance to chloride ions detect small nervous fiber in diabetic patients with good correlation with Thermotest.

The purpose of this study is to analyze the vascular side and the neurologic side on patients consulting for Erythromelalgy.

Detailed Summary:
Sponsor: Groupe Hospitalier Paris Saint Joseph

Current Primary Outcome:

• Assessment of Chlorine ion production change [ Time Frame: Day1 ]
  patient will be measured the impedance of chlorinates ions by Sudoscan
• Assessment of Temperature changing sensitivity [ Time Frame: Day1 ]
  Patients will be measured their sensitivity to temperature changing using the Thermotest

Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Groupe Hospitalier Paris Saint Joseph

Dates:
Date Received: January 31, 2017
Date Started: January 12, 2017
Date Completion: January 18, 2018
Last Updated: February 15, 2017
Last Verified: January 2017