Clinical Trial: Precision Medical Research of Non-immune Fetal Hydrops (NIFH)-From Prenatal Diagnosis to Intrauterine Treatment

Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Interventional

Official Title: Precision Medical Research of Non-immune Fetal Hydrops (NIFH)-From Prenatal Diagnosis to Intrauterine Treatment

Brief Summary: Based on multi-center clinical research resources, a large-scale prospective cohort study will be conduted to make a more accurate diagnosis and intervention plan of Non-immune fetal hydrops (NIFH), and then establish NIFH accurate treatment strategy which is suitable for China's national conditions.

Detailed Summary:

  1. Etiological study of Non-immune fetal hydrops(NIFH):

    1. Etiological study of NIFH in mid-pregnancy period;
    2. Etiological study of NIFH and hygroma colli in first trimester;
    3. Value assessment of technology for exome sequencing in diagnosis of NIFH;

  2. The accuracy of NIFH intrauterine intervention and its effect assessment:

    1. Perinatal outcomes of NIFH ;
    2. The effect of intrauterine treatments.

Sponsor: Shanghai First Maternity and Infant Hospital

Current Primary Outcome: Neonatal mortality [ Time Frame: 1 year ]

Original Primary Outcome: Same as current

Current Secondary Outcome: Success rate for the operation [ Time Frame: 1 week ]

Original Secondary Outcome: Same as current

Information By: Shanghai First Maternity and Infant Hospital

Dates:
Date Received: November 2, 2016
Date Started: December 2016
Date Completion: August 2018
Last Updated: December 9, 2016
Last Verified: November 2016