Clinical Trial: Duration of Doxycycline Treatment in EM Patients

Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Interventional

Official Title: Duration of Doxycycline Treatment in Patients With Erythema Migrans (EM). A Randomized Clinical Trial.

Brief Summary: The purpose of this study is to compare the efficacy of 7-day versus 14-day doxycycline treatment in patients with erythema migrans.

Detailed Summary:
Sponsor: University Medical Centre Ljubljana

Current Primary Outcome: Treatment outcome in patients treated for erythema migrans with doxycycline for 7 or 14 days [ Time Frame: At 12 months after enrollment. ]

Objective sequelae and post-treatment subjective new or increased symptoms (NOIS) in patients treated for erythema migrans with doxycycline for 7 or 14 days.


Original Primary Outcome: Same as current

Current Secondary Outcome: Comparison of nonspecific symptoms in patients with erythema migrans and control subjects [ Time Frame: At 12 months after enrollment. ]

Number of patients after treatment with doxycycline for 7 or 14 days for erythema migrans and number of control subjects (without a history o Lyme borreliosis) with nonspecific symptoms.


Original Secondary Outcome: Same as current

Information By: University Medical Centre Ljubljana

Dates:
Date Received: March 16, 2017
Date Started: June 1, 2017
Date Completion: June 30, 2020
Last Updated: May 12, 2017
Last Verified: May 2017