Clinical Trial: Phacoemulsification and 25 Gauge (25G) Vitrectomy Versus Phacoemulsification Only in Idiopathic Epiretinal Membranes

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Morphologic and Functional Results After Phacoemulsification and 25 Gauge Vitrectomy Versus Phacoemulsification Only in Eyes Affected by Idiopathic Epiretinal Membranes

Brief Summary: The purpose of the study is to evaluate the difference in Early Treatment Diabetic Retinopathy Study (ETDRS) visual acuity, oct retinal thickness and microperimetry in 2 groups of 30 eyes each affected by idiopathic epiretinal membranes that underwent phacoemulsification and 25G pars-plana vitrectomy with internal limiting membrane (ILM) peeling (Group 1) versus phacoemulsification only (Group 2), with a follow-up length up to 5 years.

Detailed Summary: Idiopathic epiretinal membranes represent a common cause of visual loss in elderly population. Vitrectomy with membrane peeling is nowadays considered the gold standard in the management of such pathology, with very good results either at short-time or at long-time follow up. In case of mild visual impairment due to epiretinal membrane and associated cataract, it is reasonable to treat only the lens pathology (with phacoemulsification and intra-ocular lens (IOL) implantation). In case of symptoms or ophthalmoscopic finding worsening it is always possible to submit patients who only underwent cataract surgery to vitrectomy with membrane peeling. There are, by now, no comparative studies between these two different approaches in medical literature.
Sponsor: University of Turin, Italy

Current Primary Outcome: Visual acuity (using LogMar scale) changes from baseline to pre-defined periods after surgery [ Time Frame: within 90,180,360,1360 days after surgery ]

We observed how did the visual acuity (using LogMar scale) increase after the two different surgical approaches described.


Original Primary Outcome: Same as current

Current Secondary Outcome: Microperimetry parameters and average macular thickness changes [ Time Frame: within 90,180,360,1360 days after surgery ]

We evaluated average sensitivity (SM) and local defect (DL) using microperimetry. We also evaluated the average macular thickness using optical coherence tomography technology.


Original Secondary Outcome: Same as current

Information By: University of Turin, Italy

Dates:
Date Received: December 13, 2012
Date Started: October 2006
Date Completion:
Last Updated: January 16, 2013
Last Verified: January 2013