Clinical Trial: Characteristics of Eosinophilic Gastritis, Enteritis, and Colitis in a Multi-Site Cohort

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational

Official Title: Demographics, Clinical Characteristics, and Pathology of Eosinophilic Gastritis, Enteritis, and Colitis in a Multi-Site Cohort

Brief Summary: The purpose of this study is to investigate features of patients with Eosinophilic Gastrointestinal Disorders (EGIDs) other than Eosinophilic Esophagitis (EoE) alone, including Eosinophilic Gastritis (EG), Eosinophilic Gastroenteritis (EGE), and Eosinophilic Colitis (EC).

Detailed Summary: This retrospective chart review study will analyze the demographics, medical history, clinical features, and pathological data of patients with Eosinophilic Gastrointestinal Disorders (EGIDs) other than Eosinophilic Esophagitis (EoE) alone, including Eosinophilic Gastritis (EG), Eosinophilic Gastroenteritis (EGE), and Eosinophilic Colitis (EC).
Sponsor: Children's Hospital Medical Center, Cincinnati

Current Primary Outcome: Mucosal eosinophilia (eos/hpf) [ Time Frame: Duration of funding, approximately 5 years ]

Mucosal eosinophil levels are measured as eosinophils per high power field (eos/hpf). The primary outcome measure is to determine the change in mucosal eosinophil level (eos/hpf) and to determine if the change in mucosal eosinophil level in eos/hpf correlates with other measures of disease activity.


Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Children's Hospital Medical Center, Cincinnati

Dates:
Date Received: September 2, 2016
Date Started: August 2016
Date Completion: August 2019
Last Updated: January 20, 2017
Last Verified: January 2017