Clinical Trial: Endometriosis and Brominated Flame Retardant (ENDOTOX Study)
Study Status: Completed
Recruit Status: Completed
Study Type: Observational
Official Title: Looking for a Link Between Endometriosis and Exposure to Lipophilic Environmental Chemicals Like Brominated Flame Retardant (ENDOTOX Study)
Brief Summary: The investigators wish to highlight, in a Case-Control design, if there is an increased concentration of BFRs in omental adipose tissue of cases ( women with severe endometriosis with surgical indication ) versus bioaccumulation recorded in a control cohort ( women recruited in obstetrics and gynecology or visceral surgery showing no sign of endometriosis ) . Pairing will be operate on Age (+/- 5 years compared to the case ) , BMI ( BMI 5 Classes described by the HAS) and previous breastfeeding experience (yes / no , opposite the release expected bioaccumulate contaminants in breast adipose tissue , when the lactation ) .
Detailed Summary:
Sponsor: Nantes University Hospital
Current Primary Outcome: Concentrations of brominated flame retardant (BFR) in adipose tissue and serum [ Time Frame: baseline ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Concentrations of dioxins in adipose tissue and serum [ Time Frame: baseline ]
- Concentrations of polychlorinated biphenyls (PCBs), [ Time Frame: baseline ]
- Concentrations of organochlorine pesticides (OCPs) in adipose tissue and serum [ Time Frame: baseline ]
Original Secondary Outcome: Same as current
Information By: Nantes University Hospital
Dates:
Date Received: January 6, 2016
Date Started: November 2013
Date Completion:
Last Updated: January 7, 2016
Last Verified: January 2016
