Clinical Trial: Efficacy of LNG-IUS for Treatment of Non-atypical Endometrial Hyperplasia in Perimenopausal Women

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: LNG-IUS or Norethisterone Acetate for Treatment of Non-atypical Endometrial Hyperplasia in Perimenopausal Women

Brief Summary: The purpose of this study is to compare the efficacy of the Levonorgestrel releasing Intrauterine System (Mirena) and Norethisterone Acetate for treatment of non-atypical endometrial hyperplasia in perimenopausal women.

Detailed Summary:
Sponsor: Mansoura University

Current Primary Outcome: Change in endometrial histopathology pattern from endometrial hyperplasia into regression status. [ Time Frame: At 3 and 6 months ]

Original Primary Outcome: Same as current

Current Secondary Outcome: Time to achieve complete regression [ Time Frame: During the follow up period at 3,6,12 months after treatment ]

Original Secondary Outcome: Same as current

Information By: Mansoura University

Dates:
Date Received: December 20, 2011
Date Started: May 2009
Date Completion:
Last Updated: December 22, 2011
Last Verified: December 2011