Clinical Trial: How to Improve Diagnosis in Infective Endocarditis
Study Status: Completed
Recruit Status: Completed
Study Type: Observational
Official Title: Ph. D Student, Jane Byriel Knudsen, Aarhus University
Brief Summary: The purpose is to exam prospective if simple clinical information in combination with a normal s-procalcitonin are sufficient for exclusion of infective endocarditis (IE).
Detailed Summary:
Despite progress in surgical and medical treatment, infective endocarditis is still associated with high morbidity and mortality.
The variable clinical presentation of IE makes the diagnosis a clinical challenge.
Procalcitonin is a precursor from the hormone calcitonin and also a marker of systemic bacterial infections.
The purpose of this study is:
- to investigate the diagnostic value of serum procalcitonin (PCT), C-reactive protein (CRP) and sedimentation rate (SR) when IE is suspected.
- to investigate if a retrospectively generated clinical model suitable for exclusion of IE can be confirmed prospectively.
Sponsor: University of Aarhus
Current Primary Outcome:
Original Primary Outcome:
Current Secondary Outcome:
Original Secondary Outcome:
Information By: University of Aarhus
Dates:
Date Received: August 31, 2007
Date Started: March 2007
Date Completion:
Last Updated: January 19, 2010
Last Verified: January 2010
