Clinical Trial: Urokinase Versus Video-assisted Thoracoscopic to Treat Complicated Parapneumonic Empyema in Childhood
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Exploratory Multicentre Clinical Trial to Compare the Efficacy of Urokinase Versus Video-assisted Thoracoscopic for Treatment of Complicated Parapneumonic Empyema in Child
Brief Summary: A great controversy exists about which is the best method to perform the evacuation of the collection. The purpose of this study is to evaluate which is the best initial treatment to drain complicated parapneumonic empyema (stages II and III) in children: the present study raises a hypothesis of equivalence between both arms of treatment (chest drainage plus intrapleural urokinase or videothoracoscopic debridement).
Detailed Summary:
Sponsor: Spanish Society of Pediatric Surgery
Current Primary Outcome: duration of the hospital stay after the treatment [ Time Frame: 3 months ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- complications of the treatment and complications of the disease [ Time Frame: 3 months ]
- total duration of the hospital stay [ Time Frame: 3 months ]
- number of days carrying the chest drain [ Time Frame: 3 months ]
- duration of the fever once the empyema has been drained [ Time Frame: 3 months ]
Original Secondary Outcome: Same as current
Information By: Spanish Society of Pediatric Surgery
Dates:
Date Received: November 25, 2008
Date Started: July 2008
Date Completion:
Last Updated: October 27, 2010
Last Verified: November 2008
