Clinical Trial: Assessment of Implantation Potential of Embryos by Time-lapse Technology

Study Status: Completed
Recruit Status: Unknown status
Study Type: Interventional

Official Title: Assessment of Implantation Potential of Embryos Cultured by Time-lapse Technology (Embryoscope) Before Transfer in In-vitro Fertilization (IVF) / Intracytoplasmic Sperm Injection (ICSI) Cycles: A Rand

Brief Summary:

  1. Culture conditions of developing embryos are highly controlled in the Embryoscope and are monitored by Time-lapse videography to produce 3D images at different stages.This cannot be done under conventional culture conditions.
  2. The 3D images thus produced,are analysed with the help of Embryoviewer, a part of the Embryoscope,through latest software.
  3. Embryoviewer also identifies embryos for transfer, freezing and to be discarded.

Detailed Summary:

  1. There will be two arms of the study. The Study arm in which embryos of patients will be cultured in the Embryoscope. The control arm in which the embryos of patients will be cultured under conventional conditions.
  2. Embryos to be transferred will be identified by the Embryoviewer in the Study arm and the ones in the control arm will be identified by established subjective morphological criteria.
  3. Embryos with definite implantation potential will be transferred in both arms.
  4. Embryos not transferred will be frozen and/or discarded in both arms.

Sponsor: Bloom IVF and Fertility Centre

Current Primary Outcome: No.of top quality embryos produced in both the arms, study arm and control arm. [ Time Frame: 2 weeks ]

  1. 4-cell embryos on day 2 of fertilization in both,Study arm and Control arm.
  2. 8-cell embryos on day 3 of fertilization in both Study arm and Control arm.
  3. Blastocyst embryos on day 5 or day 6 of fertilization in both Study arm and Control arm.


Original Primary Outcome: Same as current

Current Secondary Outcome: Clinical pregnancy [ Time Frame: 6 weeks after embryo transfer (ET) ]

Clinical pregnancy will be identified by presence of gestational sac(s) and fetal heart-beat by transvaginal ultrasonography in sixth week after embryo transfer.


Original Secondary Outcome: Same as current

Information By: Bloom IVF and Fertility Centre

Dates:
Date Received: December 26, 2012
Date Started: December 2012
Date Completion: April 2013
Last Updated: January 3, 2013
Last Verified: January 2013