Clinical Trial: Phenylephrine Versus Ephedrine in Pre-eclampsia

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: Impact of Vasopressor Administration on Maternal and Neonatal Outcomes in Women With Pre-eclampsia

Brief Summary: Phenylephrine administration is associated with reductions in CO and SctO2 compared with ephedrine when used for blood pressure management in women with pre-eclampsia undergoing cesarean delivery under spinal anesthesia.

Detailed Summary:
Sponsor: Duke University

Current Primary Outcome: Cerebral tissue oxygen saturation [ Time Frame: Intraoperative from spinal placement till 10 min after delivery ]

Original Primary Outcome: Same as current

Current Secondary Outcome: Cardiac output [ Time Frame: Intraoperative from spinal placement till 10 min after delivery ]

Original Secondary Outcome: Same as current

Information By: Duke University

Dates:
Date Received: December 26, 2013
Date Started: September 2012
Date Completion: January 2019
Last Updated: March 23, 2017
Last Verified: March 2017