Clinical Trial: Postpartum Uterine Curettage in the Recovery From Preeclampsia/Eclampsia

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Effects of Postpartum Uterine Curettage in the Recovery From Preeclampsia/Eclampsia: A Randomized, Controlled Trial

Brief Summary: Use of Postpartum uterine curettage in reducing hospitalization time or in improving the clinical evolution of the patient with preeclampsia/eclampsia.

Detailed Summary:

To evaluate if postpartum uterine curettage improved the clinical and laboratory parameters in patients with preeclampsia or eclampsia.

A total of 442 patients with preeclampsia/eclampsia were randomized to postpartum curettage (223) or no procedure (219). Systolic and diastolic blood pressure were recorded and analyzed at hours 6, 12, 24 and 48. Also, several laboratory values and diuresis were evaluated.


Sponsor: Saint Thomas Hospital, Panama

Current Primary Outcome:

  • Systolic and diastolic blood pressure [ Time Frame: 6 hours ]
    Arterial blood pressure
  • Systolic and diastolic blood pressure [ Time Frame: 12 hours ]
    Arterial blood pressure
  • Systolic and diastolic blood pressure [ Time Frame: 24 hours ]
    Arterial blood pressure
  • Systolic and diastolic blood pressure [ Time Frame: 48 hours ]
    Arterial Blood pressure


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Laboratory results (hypertensive disorder profile: hemoglobin, hematocrit, platelets, renal or liver function tests). [ Time Frame: 6 hours ]
    Number of patients with an abnormal laboratory value
  • Laboratory results (hypertensive disorder profile: hemoglobin, hematocrit, platelets, renal or liver function tests). [ Time Frame: 12 hours ]
    Number of patients with an abnormal laboratory value
  • Laboratory results (hypertensive disorder profile: hemoglobin, hematocrit, platelets, renal or liver function tests). [ Time Frame: 24 hours ]
    Number of patients with an abnormal laboratory value
  • Laboratory results (hypertensive disorder profile: hemoglobin, hematocrit, platelets, renal or liver function tests). [ Time Frame: 48 hours ]
    Number of patients with an abnormal laboratory value
  • Seizures [ Time Frame: 48 hours ]
    Number of participants with the development of seizures after birth.


Original Secondary Outcome: Same as current

Information By: Saint Thomas Hospital, Panama

Dates:
Date Received: January 18, 2017
Date Started: October 1, 2015
Date Completion:
Last Updated: January 20, 2017
Last Verified: January 2017