Clinical Trial: DDAVP in the Reduction of Post-operative Ecchymosis in Rhinoplasty

Study Status: Completed
Recruit Status: Unknown status
Study Type: Interventional

Official Title: A Prospective Randomized Trial for the Use of DDAVP in the Reduction of Post-operative Ecchymosis in Rhinoplasty.

Brief Summary: This is study looking at the use of a medication, Desmopressin acetate (DDAVP), to reduce bleeding, swelling, and bruising in patients undergoing cosmetic nose surgery. DDAVP is a drug used in patients with bleeding disorders. It works by activating molecules in the blood stream called platelets that promote clotting. In the study, participants who are have cosmetic nose surgery (rhinoplasty) will be randomly assigned to receive or not receive medication. Photographs taken before and shortly after surgery will be evaluated for the amount of bruising and swelling. Patients with heart, lung, kidney, or liver problems are not eligible to participate.

Detailed Summary:
Sponsor: University Hospitals Cleveland Medical Center

Current Primary Outcome: Reduction in Ecchymosis and Swelling [ Time Frame: surgery to 8 days post-operatively ]

Photographs taken preoperatively at 1 day and 8 days post-operatively will be analyzed for bruising


Original Primary Outcome: Same as current

Current Secondary Outcome: Patient Behavior Factors [ Time Frame: Surgery to 3 weeks post-operatively ]

Looking at the time it takes for patients to feel comfortable wearing makeup, going out in public, and returning to work


Original Secondary Outcome: Same as current

Information By: University Hospitals Cleveland Medical Center

Dates:
Date Received: November 5, 2013
Date Started: December 2013
Date Completion: July 2015
Last Updated: November 14, 2013
Last Verified: November 2013