Clinical Trial: LXRs, Cholesterol Metabolism and Uterine Dystocia
Study Status: Terminated
Recruit Status: Terminated
Study Type: Observational
Official Title: The Role of Two Nuclear Receptors for Oxysterols as a Molecular Cause of Uterine Dystocia: LXR Alpha and LXR Beta
Brief Summary: Despite the fact that a link between cholesterol and the myometrium has been clearly established, no study investigating aspects of cholesterol metabolism and uterine dystocia currently exists. This study is a pilot study whose aim is to test the hypothesis that an association between uterine dystocia and single-nucleotide polymorphisms (SNPs) in the genes coding for the LXRs.
Detailed Summary:
Sponsor: Centre Hospitalier Universitaire de Nīmes
Current Primary Outcome: The multi-loci genotype of the target DNA sequence. [ Time Frame: Day 1 ]
Original Primary Outcome: The genotype comprised of the homozygous of heterozygous status of the target DNA sequence for each of the polymorphisms of interest.
Current Secondary Outcome:
Original Secondary Outcome:
Information By: Centre Hospitalier Universitaire de Nīmes
Dates:
Date Received: April 14, 2010
Date Started: April 2010
Date Completion:
Last Updated: November 19, 2015
Last Verified: November 2015