Clinical Trial: Impact of Dyspnea on Patients in the Intensive Care Unit
Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational
Official Title: Impact of DYSpnea on the ouTcome of Patients Admitted for an Acute RESpiratory Failure in the intenSive Care Unit
Brief Summary: Although pain has been extensively studied in ICU patients, only a few studies have focused on dyspnea, which is experienced by 50% of mechanically ventilated patients. The purpose of the present study is to determine whether dyspnea in intensive care unit patients is associated with a higher length of stay in the ICU and a higher incidence of post traumatic stress disorders.
Detailed Summary:
Intensive care unit (ICU) patients are continuously exposed to various unpleasant sensations that are as many sources of discomfort. If, growing attention has been given to the detection and treatment of pain, very little attention has been given to dyspnea. However, there is growing evidence suggesting that dyspnea is frequent and severe in mechanically ventilated ICU patients. In mechanically ventilated ICU patients, dyspnea is independently associated with anxiety and mechanical ventilation itself. Indeed, an optimization of ventilator settings alleviates dyspnea in 35% of patients.
Various arguments suggest that dyspnea contributes to the dark experience of ICU and participates to the genesis of post traumatic stress disorders. In addition, dyspnea is associated with a longer duration of mechanical ventilation.
Large multicentre studies are however lacking. The aims of the present multicentre study are 1) to quantify the prevalence of dyspnea in a large population of ICU mechanically ventilated patients, 2) to examine the link between the level of dyspnea and the occurrence of adverse events in the ICU, 3) to determine whether dyspnea in intensive care unit patients is associated with a higher length of stay in the ICU and a higher incidence of post traumatic stress disorder associated symptoms.
Sponsor: Assistance Publique - Hôpitaux de Paris
Current Primary Outcome:
- ICU length of stay [ Time Frame: 3 months ]
- incidence of post traumatic stress disorders [ Time Frame: 3 months ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Anxiety and depression (Hamilton anxiety and depression scale) [ Time Frame: 3 months ]Hamilton anxiety and depression scale
- Quality of life (Short-Form 36) [ Time Frame: 3 months ]Short-Form 36
- Pain (Visual Analogic Scale) [ Time Frame: 3 months ]Visual Analogic Scale
- Quality of Sleep (Pittsburgh Scale) [ Time Frame: 3 months ]Pittsburgh Scale
Original Secondary Outcome: Same as current
Information By: Assistance Publique - Hôpitaux de Paris
Dates:
Date Received: January 8, 2015
Date Started: January 2016
Date Completion: February 2018
Last Updated: March 21, 2017
Last Verified: September 2016
