Clinical Trial: Identification of Correlates of Protection Against Shigella and Enterotoxigenic Escherichia Coli Infections

Study Status: Recruiting
Recruit Status: Unknown status
Study Type: Interventional

Official Title:

Brief Summary: The aim of this study is to accelerate the development of vaccine candidates against diarrheal diseases caused by Shigella and Enterotoxigenic Escherichia coli (ETEC). We plan to identify cases of laboratory-proven shigellosis and ETEC-associated diarrhea, to study humoral and cellular immune parameters following natural infections with Shigella and ETEC, and to compare the level of pre-existing local, humoral and cellular immune parameters in cases of shigellosis and ETEC-associated diarrhea and in matched controls.

Detailed Summary:
Sponsor: Hillel Yaffe Medical Center

Current Primary Outcome: Identification of cases of shigellosis and ETEC-associated diarrhea [ Time Frame: Four years ]

Stool of patients examined in laboratory and identified as infected with the pathogens


Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Hillel Yaffe Medical Center

Dates:
Date Received: July 8, 2012
Date Started: July 2012
Date Completion: July 2016
Last Updated: July 8, 2012
Last Verified: July 2012