Clinical Trial: MRI Results in Dupuytren's Contracture Before and After Injection With Xiaflex

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: MRI Results in Dupuytren's Contracture Before and After Injection With Xiaflex

Brief Summary: The purpose of this study is to determine the effects of XIAFLEX on your finger through MRI.

Detailed Summary: Collagenase injections for the treatment of Dupuytren's Contracture is a newly approved protocol which has shown early efficacy. There are very few studies which examine the MRI appearance of Dupuytren's disease. There are no studies that evaluate the condition of the cord after collagenase injection.
Sponsor: Hospital for Special Surgery, New York

Current Primary Outcome: The Measured Change in Volume of the Cord by MRI Before and After XIAFLEX Injection and Manual Manipulation. [ Time Frame: Baseline and 30 days ]

Change in Volume (millimeter cubed) of the Cord by MRI between Baseline and 30 days after XIAFLEX injection and manual manipulation.


Original Primary Outcome: The primary outcome will be the measured volume of the cord by MRI before and after XIAFLEX injection and manual manipulation. [ Time Frame: 30 days ]

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Hospital for Special Surgery, New York

Dates:
Date Received: October 10, 2011
Date Started: March 2011
Date Completion:
Last Updated: March 20, 2017
Last Verified: March 2017