Clinical Trial: Prophylactic Injection Therapy Reduces Recurrent Bleeding In Forrest Type IIb Duodenal Ulcers

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Prophylactic Injection Therapy Reduces Recurrent Bleeding Rate In Forrest Type IIb Duodenal Ulcer Bleeding

Brief Summary: The purpose of this study is to determine whether prophylactic injection therapy reduces recurrent bleeding rate for duodenal ulcers which has the endoscopic stigmata of recent bleeding.

Detailed Summary: The benefit of endoscopic therapy in ulcers with adherent clots on their surface is still uncertain. A prophylactic injection therapy may reduce the recurrent bleeding rate at this group of patients having this endoscopic stigma of recent bleeding. This type of ulcers are named as type IIb duodenal ulcers according to Forrest's classification, They cary the risk of bleeding recurrence up to 36 percent and as it is reported previously there may be a 12 fold increasement in morbidity and mortality in such cases. A prophylactic endoscopic injection therapy may reduce the risk of recurrent bleeding in this group of the patients.
Sponsor: Bakirkoy Dr. Sadi Konuk Research and Training Hospital

Current Primary Outcome: Evidence of clinically definitive recurrent bleeding confirmed by upper gastrointestinal system endoscopy or surgery. [ Time Frame: within first two days after index endoscopy ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Bakirkoy Dr. Sadi Konuk Research and Training Hospital

Dates:
Date Received: November 1, 2011
Date Started: January 2003
Date Completion:
Last Updated: November 10, 2011
Last Verified: November 2011