Clinical Trial: The Pilot Study on Tailored Eradication Therapy According to Clarithromycin Resistance in H.Pylori Patients

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: The Pilot Study on Tailored Eradication Therapy According to Clarithromycin Resistance in Helicobacter Pylori Patients

Brief Summary: This study assessed the effect of tailored eradication therapy according to Clarithromycin resistance in Helicobacter pylori patients.

Detailed Summary:

This study assessed the effect of tailored eradication therapy according to Clarithromycin resistance in Helicobacter pylori patients.

The patients with gastric or duodenal ulcer by endoscopy were registered at the study and inspected Rapid Urease test, Biopsy, IgG-Hp antibody.

The tailored eradication therapy was prescribed to patients that confirmed Helicobacter pylori positive in two or more of among the three tests for 14 days. Through this, This study is to assess the effectiveness of eradication rate and to evaluate safety and tolerability of Ilaprazole 10mg qid treatment


Sponsor: Kyungpook National University

Current Primary Outcome: Eradication rate after tailored therapy assessed by urea breath test [ Time Frame: Test at 4 -6 weeks after completion of medication ]

After completion of 14days tailored therapy, the participants will be followed at 4-6 weeks with urea breath test (UBT). The eradication rate will be assessed by the result of UBT.


Original Primary Outcome: Same as current

Current Secondary Outcome: Number of participants with treatment-related adverse events as assessed by questionnaire [ Time Frame: Questionnaire and diary during medication for 14days ]

During the medication of tailored therapy, the participants will be asked to check the compliance and adverse events with diary and questionnaire.


Original Secondary Outcome: Same as current

Information By: Kyungpook National University

Dates:
Date Received: January 5, 2016
Date Started: March 2, 2016
Date Completion:
Last Updated: February 19, 2017
Last Verified: February 2017