Clinical Trial: Platelet Rich Plasma for Frontal Fibrosing Alopecia

Study Status: NOT_YET_RECRUITING
Recruit Status: NOT_YET_RECRUITING
Study Type: INTERVENTIONAL

Official Title: Assessment of the Safety and Efficacy of Intralesional Platelet Rich Plasma in Reducing Scalp Symptoms and Promoting Hair Growth in Frontal Fibrosing Alopecia

Brief Summary: The primary objective of this study is to assess the efficacy and safety of platelet rich plasma in reducing scalp symptoms and promoting hair growth in patients diagnosed with frontal fibrosing alopecia.
Platelet rich plasma is an autologous blood product, and platelet rich plasma will be administered intralesionally for this study.
The platelet rich plasma used for this study will be prepared using the Eclipse Easy Spin centrifuge.

Detailed Summary: The primary objective of this study is to assess the efficacy and safety of platelet rich plasma in reducing scalp symptoms and promoting hair growth in patients diagnosed with frontal fibrosing alopecia.
The secondary objective of this study is subject self-assessment through the Dermatology Quality Life Index (DQLI) and Hair-Growth Assessment (HGA) as well as investigator-assessment from baseline.
Platelet rich plasma is an autologous blood product, and platelet rich plasma will be administered intralesionally for this study.
The platelet rich plasma used for this study will be prepared using the Eclipse Easy Spin centrifuge.
The duration of this study for participants is 8 months, including an initial screening visit, 6 monthly treatment visits, and a follow-up visit.
Subjects eligible for this study are those diagnosed with frontal-fibrosing alopecia via biopsy and clinical assessment.
Sponsor: University of Minnesota

Current Primary Outcome: Changes in LPPAI (LICHEN PLANOPILARIS ACTIVITY INDEX) Scale of of 0-4 0= None 4=Severe

Original Primary Outcome: Changes in LPPAI (LICHEN PLANOPILARIS ACTIVITY INDEX) Scale of of 0-4 0= None 4=Severe

Current Secondary Outcome:

Original Secondary Outcome:

Information By: University of Minnesota

Dates:
Date Received: July 27, 2017
Date Started: January 01, 2024
Date Completion: January 01, 2024
Last Updated: June 22, 2023
Last Verified: June 01, 2023