Clinical Trial: Triclosan Toothpaste and Third Molar Surgery

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Effect of a Triclosan Containing Dentifrice on Oral Bacteria and Postoperative Complications Following Third Molar Surgery

Brief Summary: Triclosan containing dentifrices are effective in the prevention of inflammatory complications following third molar surgery through reducing preoperative oral bacteria load.

Detailed Summary: This study may provide evidence on the effect of triclosan containing dentifrice on oral bacteria and oral inflammation prior to third molar surgery, and on the incidence of inflammatory complications after the surgery. If proven effective, dentifrice containing triclosan may be recommended prior to tooth extractions and replace antibiotics and other antimicrobial products as a prophylactic procedure before oral surgery procedures.
Sponsor: University of Rochester

Current Primary Outcome: dry socket [ Time Frame: 3 to 7 days ]

Development of dry socket (alveolar osteitis) 3 to 7 days after tooth extraction


Original Primary Outcome: Same as current

Current Secondary Outcome: wound infection [ Time Frame: 3 to 7 days ]

Development of tooth extraction wound infection 3 to 7 days after extraction


Original Secondary Outcome: Same as current

Information By: University of Rochester

Dates:
Date Received: February 4, 2011
Date Started: February 2008
Date Completion:
Last Updated: October 26, 2015
Last Verified: October 2015