Clinical Trial: Randomized Trial of Intranasal Versus Intravenous Naloxone in Level of Consciousness in Suspected Opioid Overdose

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Study of Routs of Naloxone Administration for Opioid Overdosed Patients

Brief Summary: The purpose of this study is to determine which route of administration is better for treatment of opioid overdosed patients

Detailed Summary: In intravenous drug abusers (IDUs), as a result of previous intravenous substance abuse, the predictable difficult cannulate exist and cause the delay administration of antidote therapy. Additionally, IDUs are also at increased risk of carrying blood borne infections that could be transmitted to healthcare workers through needle stick injuries. The investigators aimed to compare intranasal administration of naloxone with intravenous route.
Sponsor: Isfahan University of Medical Sciences

Current Primary Outcome: level of consciousness [ Time Frame: 4 min after naloxone administration ]

Original Primary Outcome: Same as current

Current Secondary Outcome: blood pressure [ Time Frame: at 4 min after naloxone administration ]

Original Secondary Outcome: Same as current

Information By: Isfahan University of Medical Sciences

Dates:
Date Received: February 9, 2011
Date Started: March 2007
Date Completion:
Last Updated: February 9, 2011
Last Verified: March 2007